San Francisco 49ers vs Indianapolis Colts NFL Week 7 Odds, Games and Outlook for October 24, 2021

October 10, 2021; Glendale, Arizona, United States; San Francisco 49ers head coach Kyle Shanahan leaves the field after the Arizona Cardinals beat the 49ers 17-10 at State Farm Stadium. Mandatory Credit: Chris Coduto-USA TODAY Sports

The San Francisco 49ers (2-3) are favored by 3.5 points as they try to break their three-game losing streak in a game against the Indianapolis Colts (2-4) on Sunday, October 24. 2021 at Levi’s Stadium. The over / under is 44 in this game.

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Odds for the 49ers vs the Colts

On / under insights

  • San Francisco’s games this season have topped 44 points three out of five times.
  • Indianapolis games are over 44 points on four of six occasions this season.
  • Sunday’s total is 2.6 points lower than the combined average of 46.6 points per game for the two teams.
  • These two teams give a combined total of 45.6 points per game, 1.6 more than the over / under in this competition.
  • The 49ers and their opponents have averaged 49.2 points per game in 2020, 5.2 more than Sunday’s total.
  • The Colts’ average total of 46.1 PPG in games this season is 2.1 points above the over / under this game.
  • San Francisco has an ATS victory in five games this year.
  • This season, the 49ers are winless ATS when they step into a game as a 3.5-point or higher favorite.
  • San Francisco games this year have exceeded points total twice on five occasions (40%).
  • The 49ers are averaging just 1.6 more points per game (23.4) than the Colts (21.8).
  • San Francisco is 0-2 ATS and 1-1 overall in games when registering more than 21.8 points.
  • The 49ers are averaging 368.2 yards per game, 1.7 more than the 366.5 the Colts allow per game.
  • When San Francisco accumulates over 366.5 yards, the team is 0-2 ATS and 1-1 overall.
  • The 49ers have seven gifts this season, while the Colts have 12 takeaways.
  • Click on SISportsbook and find the latest spread, moneyline and total for San Francisco’s game with the Colts.
  • In six Indianapolis games this season, he has four ATS wins.
  • This season, the Colts have two ATS wins in three games as an underdog by 3.5 points or more.
  • Indianapolis games this season have eclipsed the over / under on 50% of their chances (three times in six games with a set point total).
  • The Colts are just 0.6 points less per game (23.2) than the 49ers surrender (23.8).
  • Indianapolis is 4-0 ATS and 2-2 overall when the team has accumulated over 23.8 points.
  • The Colts are averaging 37.7 more yards per game (367.5) than the 49ers are giving up (329.8).
  • Indianapolis is 4-1 ATS and 2-3 overall when the team amassed over 329.8 yards.
  • This season, the Colts have returned the ball five times, three more than the 49ers to take (2).

House and route information

  • The 49ers are winless ATS (0-1) as favorites by 3.5 points or more at home.
  • The average points total in the 49ers’ home games this season is 51.3 points, 7.3 more than the over / under this game (44).
  • On the road, Indianapolis have two ATS wins and are 1-2 overall.
  • Indianapolis has exceeded the total twice in three road games this year.
  • The Colts’ away games this season are averaging 45.0 points overall, 1.0 more than the over / under this contest (44).

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